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America's Future Physicians and Medical Researchers To Visit Fox Chase Cancer Center

PHILADELPHIA (July 17, 2000) -- Top high school students from the 2000 National Youth Leadership Forum on Medicine will visit Fox Chase Cancer Center on Thursday, July 20th from 1:30 p.m. to 3:30 p.m. The 22 students, from across the country and around the world, were selected to participate in the Forum based on their outstanding academic achievements and their interest in a career in medicine.

The visit will focus on human genetics and cancer first meeting with Alfred G. Knudson, Jr., M.D., Ph.D., a senior member on the scientific research staff at Fox Chase Cancer Center. A geneticist and physician, Dr. Knudson is internationally recognized for his "two-hit" theory of cancer causation, which explained the relationship between the hereditary and non-hereditary forms of a cancer and predicted the existence of tumor-suppressor genes that can suppress cancer cell growth. This now-confirmed theory has advanced understanding of errors in the genetic program that turn normal cells into cancer cells.

Next, students will meet with genetics counselors who advise patients daily on issues concerning hereditary or familial cancers. Genetics counselors Ann Naumer and Josephine Wagner-Costalas are part of the Margaret Dyson Family Risk Assessment Program, which focuses on families with a history of breast and/or ovarian cancers.

Finally, the young scientists will visit the clinical molecular genetics lab and meet with Betsy Bove, Ph.D. to learn about genetic studies on breast and ovarian cancer. Dr. Bove and others at Fox Chase are working to associate mutations in the genes BRCA-1 and BRCA-2 with certain types of cancers in families.

The National Youth Leadership Forum on Medicine is an 11-day program, held each summer at renowned medical centers located in Boston, Chicago, Houston-Galveston, Philadelphia, San Francisco and Washington, D.C. It provides a unique educational opportunity for top high school juniors and seniors to explore some of the most prestigious and technologically advanced hospitals, research facilities and medical schools in the country. The Forum offers hands-on experience to students through large and small group activities and seminars with distinguished research pioneers and leaders of the medical community.

Fox Chase Cancer Center, one of the nation's first comprehensive cancer centers designated by the National Cancer Institute in 1974, conducts basic and clinical research; programs of prevention, detection and treatment of cancer; and community outreach. For more information about Fox Chase activities, visit the Center's web site at:

Fox Chase Cancer Center, part of the Temple University Health System, is one of the leading cancer research and treatment centers in the United States. Founded in 1904 in Philadelphia as one of the nation’s first cancer hospitals, Fox Chase was also among the first institutions to be designated a National Cancer Institute Comprehensive Cancer Center in 1974. Fox Chase researchers have won the highest awards in their fields, including two Nobel Prizes. Fox Chase physicians are also routinely recognized in national rankings, and the Center’s nursing program has received the Magnet recognition for excellence four consecutive times. Today, Fox Chase conducts a broad array of nationally competitive basic, translational, and clinical research, with special programs in cancer prevention, detection, survivorship, and community outreach.  For more information, call 1-888-FOX CHASE or (1-888-369-2427).

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