Table of Services

Molecular Modeling Publications

Molecular Modeling Publications

  • Tong X, Zitserman D, Serebriiskii I, Andrake M, Dunbrack R, Roegiers F. Numb independently antagonizes Sanpodo membrane targeting and Notch signaling in Drosophila sensory organ precursor cells. Mol Biol Cell. 2010 Mar 1;21(5):802-10. PMCID: PMC2828966
  • Li C, Andrake M, Dunbrack R, Enders GH. A bifunctional regulatory element in human somatic Wee1 mediates cyclin A/Cdk2 binding and Crm1-dependent nuclear export. Mol Cell Biol. 2010 Jan;30(1):116-30. PMCID: PMC2798281
  • Banumathy G, Somaiah N, Zhang R, Tang Y, Hoffmann J, Andrake M, Ceulemans H, Schultz D, Marmorstein R, Adams PD. Human UBN1 is an ortholog of yeast Hpc2p and has an essential role in the HIRA/ASF1a chromatin-remodeling pathway in senescent cells. Mol Cell Biol. 2009 Feb;29(3):758-70. PMCID: PMC2630694
  • Pietsch EC, Perchiniak E, Canutescu AA, Wang G, Dunbrack RL, Murphy ME. Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain. J Biol Chem. 2008 Jul 25;283(30):21294-304. PMCID: PMC2475706
  • Robinson MK, Hodge KM, Horak E, Sundberg AL, Russeva M, Shaller CC, von Mehren M, Shchaveleva I, Simmons HH, Marks JD, Adams GP. Targeting ErbB2 and ErbB3 with a bispecific-single chain Fv enhances targeting selectivity and induces a therapeutic effect in vitro. Br J Cancer. 2008 Nov 4;99(9):1415-25. PMCID: PMC2576487
  • Wang Q, Canutescu AA, Dunbrack RL Jr. SCWRL and MolIDE: Programs for protein side-chain prediction and homology modeling. Nat Protoc. 2008;3(12):1832-47. PMCID: PMC2682191
  • Pimkin M, Caretti E, Canutescu A, Yeung JB, Cohn H, Chen Y, Oleykowski C, Bellacosa A, Yeung AT. Recombinant nucleases CEL I from celery and SP I from spinach for mutation detection. BMC Biotechnol. 2007 Jun 1;7:29.
  • Samuel D, Cheng H, Riley PW, Canutescu AA, Nagaswami C, Weisel JW, Bu Z, Walsh PN, Roder H. Solution structure of the A4 domain of factor XI sheds light on the mechanism of zymogen activation. Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15693-8.
  • Tang Y, Poustovoitov MV, Zhao K, Garfinkel M, Canutescu A, Dunbrack RL, Jr, Adams PD, Marmorstein R. Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly. Nat Struct Mol Biol. 2006;13:921-929.
  • Krasley E, Cooper KF, Mallory MJ, Dunbrack R, Strich R. Regulation of the oxidative stress response through Slt2p-dependent destruction of cyclin C in Saccharomyces cerevisiae. Genetics. 2006 Mar;172(3):1477-86.
  • Xu Q, Canutescu A, Obradovic Z, Dunbrack RL Jr. ProtBuD: a database of biological unit structures of protein families and superfamilies. Bioinformatics. 2006 Dec 1;22(23):2876-82.
  • Tarn C, Merkel E, Canutescu AA, Shen W, Skorobogatko Y, Heslin MJ, Eisenberg B, Birbe R, Patchefsky A, Dunbrack R, Arnoletti JP, von Mehren M, Godwin AK. Analysis of KIT mutations in sporadic and familial GIST: therapeutic implications using protein modeling. Clin Cancer Res. 2005 May 15;11(10):3668-77.
  • Canutescu AA, Dunbrack RL, Jr. MOLIDE: a homology modeling program you can click with. Bioinformatics. 2005;21:2914-6.
  • Zhang R, Poustovoitov MV, Ye X, Santos HA, Chen W, Daganzo SM, Erzberger JP, Serebriiskii IG, Canutescu AA, Dunbrack RL, Pehrson JR, Berger JM, Kaufman PD, Adams PD. Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA. Dev Cell. 2005 Jan;8(1):19-30.
  • Cheng JD, Valianou M, Canutescu AA, Jaffe EK, Lee HO, Wang H, Lai JH, Bachovchin WW, Weiner LM. Abrogation of fibroblast activation protein enzymatic activity attenuates tumor growth. Mol Cancer Ther. 2005 Mar;4(3):351-60.