Cytogenetics and Chromosome Microarray Analysis Services
Cytogenetic analysis of human, mouse and rat chromosomes
Cell line species verification; computation of modal chromosome number; karyotypic analysis of blood, bone marrow, solid tumors, and cell lines; mapping the location of viral or transgene integrations, identification of chromosomal breakpoints, and detection of amplified or deleted genes in human, rat, and mouse metaphases by fluorescence in situ hybridization (FISH); interphase FISH; and chromosome painting and multiplex-FISH (M-FISH) to facilitate the interpretation of chromosome rearrangements.
DNA copy number analysis; genomic analysis
Utilization of Affymetrix platform for various DNA copy number and loss of heterozygosity (LOH) analyses, pharmacogenetics, and promoter methylation studies. SNP analysis for GWAS, using the Affymetrix platform, and array-CGH analysis of murine or human samples, using Agilent's DNA microarray-based technology.