Faculty Summaries
James S. Duncan, PhD
James S. Duncan, PhD
Assistant Professor
Office Phone: 215-728-2565
Lab Phone: 215-728-2565
Office: P3039

Exploring the cancer kinome through chemical proteomics

  • Unlocking the therapeutic potential of the "untargeted kinome."
  • Designing novel combination therapies for the treatment of cancer.
Description of research projects
Selected Publications

Fox Chase Programs

    1. Duncan, JS. Whittle, MC. Nakamura, K. Abell, AN. Midland, AA. Zawistowski, JS. Johnson, NL. Granger, DA. Vincent, NJ. Darr, DB. Usary, J. Kuan, PF. Smalley, DM. Major, B. He, X. Hoadley, K. Zhou, B. Sharpless, NE. Perou, CM. Kim, WY. Gomez, SM. Chen, X. Jin, J. Frye, SV. Earp, HS. Graves, LM. Johnson, GL. (2012) Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple negative breast cancer. Cell. 149(2): 307-321.
    3. Duncan, JS. Turowec, JP. Wu, C. Duncan, KE. Vilk, G. Wu, C. Luscher, B. Li, SC. Gloor, GB. Litchfield, DW. (2011) A peptide-based target screen implicates the protein kinase CK2 in the global regulation of caspase signaling. Sci Signal, 4(172): ra30.
All publications